In a landmark partnership announced on October 1, 2025, Spotify has opened its vast audio and video ad inventory to Amazon's Demand-Side Platform (DSP), enabling programmatic buying for the first time. This deal promises to supercharge programmatic audio advertising by blending Amazon's shopper data with Spotify's 696 million engaged listeners, potentially lowering costs, boosting reach, and transforming how brands target music-streaming audiences. This article explores the mechanics of the agreement, its immediate benefits, and the broader ripple effects on the evolving audio ad landscape.